Many believe that the ethical problems of donation after cardiocirculatory death (DCD) have been "worked out" and that it is unclear why DCD should be resisted. In this paper we will argue that DCD donors may not yet be dead, and therefore that organ donation during DCD may violate the dead donor rule. We first present a description of the process of DCD and the standard ethical rationale for the practice. We then present our concerns with DCD, including the following: (...) irreversibility of absent circulation has not occurred and the many attempts to claim it has have all failed; conflicts of interest at all steps in the DCD process, including the decision to withdraw life support before DCD, are simply unavoidable; potentially harmful premortem interventions to preserve organ utility are not justifiable, even with the help of the principle of double effect; claims that DCD conforms with the intent of the law and current accepted medical standards are misleading and inaccurate; and consensus statements by respected medical groups do not change these arguments due to their low quality including being plagued by conflict of interest. Moreover, some arguments in favor of DCD, while likely true, are "straw-man arguments," such as the great benefit of organ donation. The truth is that honesty and trustworthiness require that we face these problems instead of avoiding them. We believe that DCD is not ethically allowable because it abandons the dead donor rule, has unavoidable conflicts of interests, and implements premortem interventions which can hasten death. These important points have not been, but need to be fully disclosed to the public and incorporated into fully informed consent. These are tall orders, and require open public debate. Until this debate occurs, we call for a moratorium on the practice of DCD. (shrink)

Since the introduction of a new criterion for determining death (i.e., the brain death criterion) in 1968, the research community has been embroiled in debates about whether this criterion should b...

In their target article, titled “The Place of Philosophy in Bioethics Today” (Blumenthal-Barby et al. 2022), Jennifer Blumenthal-Barby and colleagues provide a powerful argument for the role of phi...

BackgroundThe nature of a woman’s orgasm has been a source of scientific, political, and cultural debate for over a century. Since the Victorian era, the pendulum has swung from the vagina to the clitoris, and to some extent back again, with the current debate stuck over whether internal sensory structures exist in the vagina that could account for orgasms based largely on their stimulation, or whether stimulation of the external glans clitoris is always necessary for orgasm.MethodWe review the history of (...) the clitoral versus vaginal orgasm debate as it has evolved with conflicting ideas and data from psychiatry and psychoanalysis, epidemiology, evolutionary theory, feminist political theory, physiology, and finally neuroscience.ResultsA new synthesis is presented that acknowledges the enormous potential women have to experience orgasms from one or more sources of sensory input, including the external clitoral glans, internal region around the “G-spot” that corresponds to the internal clitoral bulbs, the c... (shrink)

We argue that the propositional and link-based approaches to human contingency learning represent different levels of analysis because propositional reasoning requires a basis, which is plausibly provided by a link-based architecture. Moreover, in their attempt to compare two general classes of models (link-based and propositional), Mitchell et al. refer to only two generic models and ignore the large variety of different models within each class.

In this paper I undermine the Entailment Principle according to which if an entity is a truthmaker for a certain proposition and this proposition entails another, then the entity in question is a truthmaker for the latter proposition. I argue that the two most promising versions of the principle entail the popular but false Conjunction Thesis, namely that a truthmaker for a conjunction is a truthmaker for its conjuncts. One promising version of the principle understands entailment as strict implication but (...) restricts the field of application of the principle to purely contingent truths (i.e. those that contain no necessary proposition at any level of analysis). But a conjunction of purely contingent truths strictly implies its conjuncts. So this version of the principle is committed to the Conjunction Thesis. The same is true of the version of the principle where entailment is understood in the sense of systems T, R, and E of relevant logic, since in these systems conjunctions entail their conjuncts. I argue that the Conjunction Thesis is false because a truthmaker is that in virtue of what a certain proposition is true and it is false that, for example, what the proposition that Peter is a man is true in virtue of is the conjunctive fact that Peter is man and Saturn is a planet (or the facts that Peter is a man and that Saturn is a planet taken together). I also argue against other versions of the principle. (shrink)

In this paper two deductive systems associated with relevance logic are studied from an algebraic point of view. One is defined by the familiar, Hilbert-style, formalization of R; the other one is a weak version of it, called WR, which appears as the semantic entailment of the Meyer-Routley-Fine semantics, and which has already been suggested by Wójcicki for other reasons. This weaker consequence is first defined indirectly, using R, but we prove that the first one turns out to be an (...) axiomatic extension of WR. Moreover we provide WR with a natural Gentzen calculus. It is proved that both deductive systems have the same associated class of algebras but different classes of models on these algebras. The notion of model used here is an abstract logic, that is, a closure operator on an abstract algebra; the abstract logics obtained in the case of WR are also the models, in a natural sense, of the given Gentzen calculus. (shrink)

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BackgroundAlthough humans experience orgasms with a degree of statistical regularity, they remain among the most enigmatic of sexual responses; difficult to define and even more difficult to study empirically. The question of whether animals experience orgasms is hampered by similar lack of definition and the additional necessity of making inferences from behavioral responses.MethodHere we define three behavioral criteria, based on dimensions of the subjective experience of human orgasms described by Mah and Binik, to infer orgasm-like responses in other species: 1) (...) physiological criteria that include pelvic floor and anal muscle contractions that stimulate seminal emission and/or ejaculation in the male, or that stimulate uterine and cervical contractions in the female; 2) short-term behavioral changes that reflect immediate awareness of a pleasurable hedonic reward state during copulation; and 3) long-term behavioral changes that depend on the reward state induced by the OLR, including sexual sat... (shrink)

Leibniz’s short letter to the mathematician and physicist Ludovico Casati of 1689 is a short but interesting text on the Principle of Identity of Indiscernibles, to which it is entirely dedicated. Since there is no watermark in the paper of the letter, the letter is difficult to date, but it is likely that it was written during Leibniz’s stay in Rome, sometime between April and November of 1689 (A 2 2 287–8). When addressing the letter, Leibniz wrote ‘Casani’, but this (...) seems to be a mistake and the real addressee is thought to be Ludovico Casati, nephew of Paolo Casati, the Jesuit mathematician. The letter, reproduced in the Berlin’s Academy edition of Leibniz’s works, was first published by Gerhardt in the Archiv für Geschichte der Philosophie in 1892 (Gerhardt 1892: 53–54). It also appears in Robinet’s Iter Italicum (Robinet 1988: 134–35). But neither Gerhardt nor Robinet provide a philosophical discussion of the letter, and I am not aware of any other philosophical discussion of it. Furthermore, as far as I know, the letter has never been translated into any language. Thus I shall here provide a transcription (from A 2 2 288–89) and a translation of the letter into English, and a philosophical discussion of its treatment of the Identity of Indiscernibles. (shrink)

El artículo presenta las principales corrientes y aportaciones del constructivismo social en la ciencia y la tecnología. Reconoce su contribución al ofrecer una imagen de la ciencia como una empresa colectiva y reivindicar una mayor flexibilidad de las interpretaciones y evidencias científico-tecnológicas. Para ello, señala que lo que caracteriza a estas corrientes es un ateísmo o agnosticismo epistemológico. Indica que, paradójicamente, para aprovechar las aportaciones del constructivismo a la ciencia, y también a la ciencia social, es necesario adoptar un compromiso (...) epistemológico que conlleva implicarse en un proceso en el que es preciso ofrecer criterios con los que sea posible reconocer qué evidencia es más robusta o qué métodos y teorías resultan más potentes. (shrink)

La antigüedad de la escritura china es bien conocida en Occidente, hasta el punto de constituir uno de los clichés con los que nos representamos al gran país asiático. Pero ¿qué significa para China el acto de escribir? ¿Cómo ha pensado el texto la civilización que desde más antiguo lo cultivó? Liu Xie, uno de los grandes tratadistas de la Antigüedad, monje budista y oficial del Gobierno durante la dinastía Liang, nos ofrece algunas claves fundamentales al respecto. En su célebre (...) obra Wen Xin Diao Long, y tras haber establecido en un primer momento el inestimable valor de las obras del canon confuciano, este autor parece chocar varias veces con el problema del «nuevo texto». Apresado entre el valor literario de la originalidad y la perversidad inaceptable de la desviación (respecto al canon), el letrado va formando un particular sentido de la producción textual, a cuyo procedimiento correspondiente denomino «variación». Esta misma lógica de la producción literaria se puede rastrear en las obras de otros letrados y aún en otras disciplinas distintas de la escritura, constituyendo así una noción trasversal del pensamiento chino. (shrink)

CONTENIDO: Itinerarios nietzscheanos / Aníbal Córdoba M. / - Nietzscher y la historia / Luis Antonio Restrepo A. / - Lenguaje, genealogía e interpretación / Jairo Montoya G. / - El amor y la muerte en la vida y el pensamiento de Nietzsche / Carlos Mario González R. / - La caverna de la interpretación / Jorge Mario Mejía T. / - Genealogía y poder / Jean Paul Margot / - Nietzche y la escritura / Jorge Alberto Naranjo M. / (...) - Salud, enfermedad, música. Reflexiones sobre la filosofía de Friedrich Nietzsche / Javier Escobar I / - Nietzche y Deleuze: encuentros / Juan Gonzalo Moreno V. (shrink)

Published in 1998, the main aim of this book is to use a naturalistic, evolutionary approach to solve some of the most important problems in philosophy. The first two problems come from the philosophy of science: the problem of rationality of science and the problem of truth in science. In presenting the first problem, the author argues that the views of Kuhn and Feyerabend do create a very serious challenge to traditional epistemology, however, if the assumption of individual rationality is (...) abandoned in favour of the author's social concept of rationality, a committed naturalism can account for science as a rational activity. In tackling the second problem of truth, the author shows that a committed evolutionary philosophy does not support realism but leads instead to a thorough evolutionary relativism of scientific knowledge. It is nevertheless possible to use this evolutionary relativism to construct a theory of relative truth. The issue of whether science discovers truth has also been tied to absolutism, that a well formulated theory of relative truth is likely to bring about a profound transformation of the way we think about the field. The author explores the notion of relative truth in the philosophy of science, ethics and aesthetics. (shrink)

The aim of this paper is to introduce a new approach to the modal operators of necessity and possibility. This approach is based on the existence of two negations in certain lattices that we call bi-Heyting algebras. Modal operators are obtained by iterating certain combinations of these negations and going to the limit. Examples of these operators are given by means of graphs.

The hypothesis that this paper seeks to propose is that, despite all the difficulties for its conceptualization, Bataille postulates that the community is, after all, possible. To do this, we will seek to study the place of the community in Bataille's thought, a place that is not precisely identifiable at all, but rather is scattered throughout his work at different points. Thus, we will try, in the first instance, to analyze how a lost community appears in the French philosopher, in (...) order to, in a second place, investigate what was the - misguided - fascist response to that fact, and, finally, outline how it could erect a proactive model of community according to Bataille. (shrink)

The publication of scientific papers has become increasingly problematic in the last decades. Even if we agree that a renewed model is needed for peer-reviewed scientific publication, we think the problem does not essentially lie in professional publishing—with economic incentives—but in the publish-or-perish culture that dominates the lives of researchers and academics.

Gonzalo Rodriguez-Pereyra offers a fresh philosophical account of properties. How is it that two different things (such as two red roses) can share the same property (redness)? According to resemblance nominalism, things have their properties in virtue of resembling other things. This unfashionable view is championed with clarity and rigor.

This text has already been published in Time & Society, 2016, Vol. 25, pp. 613-633. We thank Gonzalo Iparraguirre for the permission to republish it here.: This article presents the introduction and the update of an ethnographic research on temporality among indigenous groups, published in 2011 in its full version as a book in Spanish. It seeks to prove the usefulness of the conceptual distinction between time, defined as the phenomenon of becoming in itself, and - Anthropologie – Nouvel (...) article. (shrink)

This article deals with a modern disease of academic science that consists of an enormous increase in the number of scientific publications without a corresponding advance of knowledge. Findings are sliced as thin as salami and submitted to different journals to produce more papers. If we consider academic papers as a kind of scientific ‘currency’ that is backed by gold bullion in the central bank of ‘true’ science, then we are witnessing an article-inflation phenomenon, a scientometric bubble that is most (...) harmful for science and promotes an unethical and antiscientific culture among researchers. The main problem behind the scenes is that the impact factor is used as a proxy for quality. Therefore, not only for convenience, but also based on ethical principles of scientific research, we adhere to the San Francisco Declaration on Research Assessment when it emphasizes “the need to eliminate the use of journal-based metrics in funding, appointment and promotion considerations; and the need to assess research on its own merits rather on the journal in which the research is published”. Our message is mainly addressed to the funding agencies and universities that award tenures or grants and manage research programmes, especially in developing countries. The message is also addressed to well-established scientists who have the power to change things when they participate in committees for grants and jobs. (shrink)

Heterogeneity within MDD has hampered identification of biological markers (e.g., intermediate phenotypes, IPs) that might increase risk for the disorder or reflect closer links to the genes underlying the disease process. The newer characterizations of dimensions of MDD within Research Domain Criteria (RDoC) domains may align well with the goal of defining IPs. We compare a sample of 25 individuals with MDD compared to 29 age and education matched controls in multimodal assessment. The multimodal RDoC assessment included the primary IP (...) biomarker, positron emission tomography (PET) with a selective radiotracer for 5-HT1A ([11C]WAY-100635), as well as event-related functional MRI with a Go/No-go task targeting the Cognitive Control network, neuropsychological assessment of affective perception, negative memory bias and Cognitive Control domains. There was also an exploratory genetic analysis with the serotonin transporter (5-HTTLPR) and monamine oxidase A (MAO-A) genes. In regression analyses, lower 5-HT1A binding potential (BP) in the MDD group was related to diminished engagement of the Cognitive Control network, slowed resolution of interfering cognitive stimuli, one element of Cognitive Control. In contrast, higher/normative levels of 5-HT1A BP in MDD (only) was related to a substantial memory bias toward negative information, but intact resolution of interfering cognitive stimuli and greater engagement of Cognitive Control circuitry. The serotonin transporter risk allele was associated with lower 1a BP and the corresponding imaging and cognitive IPs in MDD. Lowered 5HT 1a BP was present in half of the MDD group relative to the control group. Lowered 5HT 1a BP may represent a subtype including decreased engagement of Cognitive Control network and impaired resolution of interfering cognitive stimuli. Future investigations might link lowered 1a BP to neurobiological pathways and markers, as well as probing subtype-specific treatment targets. (shrink)

In this article, we aim at presenting a thorough and comprehensive explanation of the mathematical and theoretical relation between all the aspects of Ptolemaic planetary models and their counterparts which are built according to Kepler’s first two laws. Our article also analyzes the predictive differences which arise from comparing Ptolemaic and these ideal Keplerian models, making clear distinctions between those differences which must be attributed to the structural variations between the models, and those which are due to the specific parameters (...) Ptolemy determined in the Almagest. We expect that our work will be a contribution for a better understanding not only of the Ptolemaic theories for planetary longitudes through a clearer perception of the way in which Keplerian features are present—or absent—in Ptolemy’s models, but also for a more balanced judgement of different aspects of the contribution of the first two laws of Kepler to the modern astronomical revolution. (shrink)

The digital transfer of the mind to a computer system requires representing the mind as a finite sequence of bits. The classic “stored-program computer” paradigm, in turn, implies the equivalence between program and data, so that the sequence of bits themselves can be interpreted as a program, which will be algorithmically executed in the receiving device. Now, according to a previous proof, on which this paper is based, a computational or algorithmic machine, however complex, cannot be free. Consequently, a finite (...) sequence of bits cannot adequately represent a free mind and, therefore, a free mind cannot be digitally transferred, quod erat demonstrandum. The impossibility of making this transfer, as demonstrated here, should be a concern especially for those who wish to achieve it. Since we intend this to be a rigorous demonstration, we must give precise definitions and conditions of validity. The most important part of the paper is devoted to explaining the meaning and reasonableness of these definitions and conditions. Special attention is paid, also, to the philosophical implications of the demonstration. Finally, this thesis is distinguished from other closely related issues. (shrink)

In this study, we propose considering membership in the Ethics Officer Association (EOA) as a proxy for the firm's commitment to ethical decision making, and we analyze the influence of firm- and CEO-specific characteristics on this commitment. While we observe a positive relationship between membership and firm size, we also document a negative relationship between EOA membership and the executive's time in position and, to a more modest extent, accounting returns. Pursuing this further, we present evidence that firms with past (...) legal issues may seek EOA membership as a signal of their intention to be compliant in the future. (shrink)

In this study, we propose considering membership in the Ethics Officer Association (EOA) as a proxy for the firm's commitment to ethical decision making, and we analyze the influence of firm- and CEO-specific characteristics on this commitment. While we observe a positive relationship between membership and firm size, we also document a negative relationship between EOA membership and the executive's time in position and, to a more modest extent, accounting returns. Pursuing this further, we present evidence that firms with past (...) legal issues may seek EOA membership as a signal of their intention to be compliant in the future. (shrink)

In this study, we propose considering membership in the Ethics Officer Association (EOA) as a proxy for the firm''s commitment to ethical decision making, and we analyze the influence of firm- and CEO-specific characteristics on this commitment. While we observe a positive relationship between membership and firm size, we also document a negative relationship between EOA membership and the executive''s time in position and, to a more modest extent, accounting returns. Pursuing this further, we present evidence that firms with past (...) legal issues may seek EOA membership as a signal of their intention to be compliant in the future. (shrink)

Este estudio aborda el conocimiento y el trabajo matemático del profesor durante la enseñanza de las representaciones de la función a través del uso en conjunto de dos modelos teóricos. Se analiza una sesión para el 1er año de enseñanza media (14-15 años) dada por un profesor de matemática con la categoría de experto. Los resultados dan cuenta de la relación entre el trabajo matemático que se propone en el aula y los conocimientos que permiten esta organización, aportando elementos a (...) la comprensión de la práctica docente. (shrink)